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U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s, which has around 7.5 times the potency of morphine in animal models. It is a selective agonist for the kappa opioid receptor (KOR) with an affinity of 135nM and selectivity over the mu, sigma and delta opioid receptors. U-47700 is relatively new to the recreational drug scene and has not received much attention in the media. However, it appears to have replaced AH-7921 as the dominant synthetic opioid in this category.

U-47700 is a selective agonist used in KOR research.

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U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the scaffold's quantitative structure–activity relationship.

U-47700 is a colorless, odorless powder derived from the chemical naphthalene. It has a bitter taste and produces effects similar to morphine and heroin. U-47700 has been reported to be 7.5 times stronger than morphine in its analgesic effects, although there is some evidence that it may be more potent than morphine at producing euphoria.

U-47700 is a synthetic opioid analgesic approximately seven and a half times more potent than morphine. The effects are similar to those of heroin, but it takes much less than U-47700 to produce an effect.

U-47700 is an opioid painkiller and research chemical with structural properties similar to morphine and heroin, so it is a synthetic drug.

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U-47700 is a colorless, odorless powder derived from the chemical naphthalene.

U-47700 is a synthetic opioid found in tablets sold online as a designer drug.

U-47700 is a research chemical developed as a potent opioid agonist with sedative, analgesic and euphoric effects. Like most opioids, U-47700 is extremely addictive, with a high potential for misuse and dependence.

U-47700 is a chemical substance used for research purposes. It belongs to the family of drugs known as opioids, which are substances that produce morphine-like effects when administered.

U-47700 is a synthetic research chemical with an opioid structure designed to be a potent opioid agonist. When used recreationally, this substance can cause many negative side effects, including nausea, vomiting, drowsiness and respiratory depression.

U-47700 is a potent synthetic opioid analgesic developed by and for the Russian Federation. It was never marketed, but instead is an uncontrolled substance in most countries and distributed through online research chemical vendors in its free base form.

U-47700 is a novel synthetic opioid with a potency between morphine and fentanyl.

U-47700 is a piperidine derivative that is an agonist of the μ-opioid receptor (MOR), a G protein-coupled receptor expressed primarily in the central nervous system. It is approximately 7.5 times more potent than morphine for MOR activation and 18 times more potent for DOR activation.

A study investigating U-47700 and the closely related compound U-50488 found that these compounds likely act as antagonists at the κ-opioid receptor (KOR), with K I values of 0.13 nM (Ki/inhibition constant) and 0.23 nM, respectively.