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Specification
Product Name: 5-MeO-DALT
IUPAC Name: N-Allyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]prop-2-en-1-amine
Other Names: 5-MeO-DALT, Foxtrot
Molecular Formula: None
Molar Mass: 237.26 g·mol−1
Effect: stimulant, psychedelic
Purity of the substance: 99.9%
Physical properties: Crystals, Powder
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Table of Contents

  1. Introduction
  2. Chemistry
  3. Pharmacology
  4. Dosage
  5. Physical Effects
  6. Cognitive Effects
  7. Toxicity and Harm Potential
  8. Tolerance and Addiction Potential
  9. Dangerous Interactions
  10. Legal Status

Origins and Synthesis

N,N-Diallyl-5-methoxytryptamine, commonly known as 5-MeO-DALT or colloquially as Foxtrot, belongs to the tryptamine class of psychedelics. It was first synthesized by Alexander Shulgin, a renowned chemist in the field of psychoactive substances. Shulgin shared the initial findings regarding the synthesis and effects of 5-MeO-DALT with a researcher in May 2004. Subsequently, this information circulated online, leading to its emergence in the online research chemical market. Formal documentation of the synthesis and effects was published by Erowid in August 2004.

Emergence and Detection

Reports of the detection of 5-MeO-DALT began to surface in 2007, marking its entry into the sphere of psychoactive substances.

Effects and Characteristics

Anecdotal reports suggest that 5-MeO-DALT primarily induces physical effects, distinguishing it from other psychedelics like 5-MeO-DiPT and DALT. Unlike typical psychedelics, it reportedly lacks profound visual distortions or perceptual depth. Its headspace is described as "shallow," though it is noted for its potent stimulating and libidinous effects. These effects make it particularly suited for contexts involving sexual activity. However, users have reported uncomfortable cardiovascular effects, including increased blood pressure and heart rate, raising concerns about potential toxicity associated with prolonged or heavy use.

Pharmacological Properties and Safety Considerations

Limited data exists regarding the pharmacological properties, metabolism, and toxicity of 5-MeO-DALT. Furthermore, its relatively short history of human use underscores the need for caution. Given the lack of comprehensive understanding, it is highly advised to practice harm reduction measures when using this substance.

Understanding the Chemistry of 5-MeO-DALT

Chemical Structure and Relation to Other Compounds

The chemical name of 5-MeO-DALT is N-allyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl] prop-2-en-1-amine. It shares structural similarities with compounds like 5-MeO-DPT and DALT (N,N-Diallyltryptamine). The name "5-MeO-DALT" is derived from its chemical structure, representing "5-MethOxy-DiALlylTryptamine." It features two allyl groups attached to the amino group and a 5-methoxy group linked to the indole ring of tryptamine. This compound is an off-white powder at room temperature.

Exploring Pharmacology

5-MeO-DALT interacts with various receptors in the brain, including:

  • 5-HT1A
  • 5-HT1D
  • 5-HT1E
  • 5-HT2A
  • 5-HT2B
  • 5-HT2C
  • 5-HT6
  • α2A
  • α2B
  • α2C
  • H1
  • κ-opioid
  • σ1
  • σ2

It exhibits binding to these receptors with Ki values lower than 10μM and acts as a monoamine reuptake inhibitor for DAT and SERT.

Mechanism of Action

As a partial agonist of the 5-HT2A receptor, 5-MeO-DALT's psychedelic effects are believed to stem from its activity at these receptors. However, the precise mechanisms underlying its psychedelic properties are still under investigation in scientific research.

Additionally, 5-MeO-DALT has been utilized as an intermediate compound in the synthesis of radiolabeled diethyltryptamine.

Subjective Effects

Disclaimer: The effects mentioned below are based on anecdotal reports from users and the analysis of contributors to the Subjective Effect Index (SEI). It's essential to approach these effects with caution and skepticism, as they may not occur predictably or reliably. Higher doses are more likely to induce the full spectrum of effects, while adverse effects, including addiction or severe harm, become increasingly probable at higher doses.

Understanding Dosage of 5-MeO-DALT

Threshold Dosage

The threshold dosage for 5-MeO-DALT is typically reported to be around 4 milligrams. At this level, users may begin to perceive subtle effects, although they may not be pronounced or easily noticeable.

Light Dosage

A light dosage of 5-MeO-DALT falls within the range of 5 to 12 milligrams. At this dosage, users may experience mild effects that are perceptible but not overwhelming. These effects may include slight alterations in perception and mood.

Common Dosage

The common dosage range for 5-MeO-DALT is typically between 12 to 25 milligrams. At this level, users can expect moderate effects that are more pronounced than at lower dosages. Visual distortions, changes in cognition, and alterations in sensory perception may become more apparent.

Strong Dosage

A strong dosage of 5-MeO-DALT typically ranges from 25 to 35 milligrams. At this level, users may experience intense psychedelic effects that can be profound and potentially overwhelming. Visual hallucinations, profound changes in perception, and alterations in consciousness are commonly reported.

Heavy Dosage

Dosages exceeding 35 milligrams of 5-MeO-DALT are considered heavy. At this level, users may experience extremely intense and potentially uncomfortable effects. The psychedelic experience may become overwhelming, and users may encounter challenges maintaining a coherent sense of reality. It's essential to approach dosages at this level with extreme caution due to the increased risk of adverse effects and potential harm.

Understanding the Physical Effects of 5-MeO-DALT

Stimulation

  • Spontaneous Physical Sensations: Users often report experiencing a motionless, constant, sharp, and all-encompassing tingling sensation, known as the "body high." This sensation gradually intensifies during the come-up phase and reaches its peak during the peak effects.

  • Tactile Enhancement: Users may notice an enhancement in tactile sensations, making textures and physical sensations more pronounced and enjoyable.

  • Increased Heart Rate: There are anecdotal reports of 5-MeO-DALT causing an increase in heart rate, although further research is needed to confirm this effect.

  • Increased Blood Pressure: Similarly, some users report experiencing an increase in blood pressure after consuming 5-MeO-DALT, although empirical evidence is lacking.

  • Temperature Regulation Suppression: Users may experience a suppression of normal temperature regulation mechanisms, potentially leading to sensations of warmth or coldness.

  • Pupil Dilation: Like many other psychedelics, 5-MeO-DALT can cause pupil dilation, resulting in larger than usual pupils.

Visual Effects

  • Enhancements: Users may experience enhancements in visual perception, including increased acuity, color intensity, and pattern recognition.

  • Distortions: Visual distortions such as drifting (melting, flowing, breathing, and morphing), color shifting, symmetrical texture repetition, tracers, and geometric patterns are commonly reported.

  • Geometry: The visual geometry experienced with 5-MeO-DALT is often described as similar to that of AMT (alpha-methyltryptamine), featuring unstructured organization, synthetic geometric style, intricate complexity, small size, slow and smooth motion, colorful schemes, glossy colors, and blurred yet sharp edges. The corners may be both rounded and angular. The compound may produce geometry comparable to level 8A or 8B at heavy doses, although this has not been confirmed.

Cognitive Effects

  • Headspace: Users typically describe the cognitive effects of 5-MeO-DALT as insightful and relatively normal in thought processes, even at moderate to high doses.

  • Analysis Enhancement: There may be an enhancement in analytical thinking, allowing users to process information more deeply or from different perspectives.

  • Emotion Enhancement: Emotions may become more intense and profound under the influence of 5-MeO-DALT.

  • Increased Libido: Users often report a significant increase in libido or sexual desire while under the influence of the substance.

  • Increased Music Appreciation: Music may be perceived as more enjoyable or profound, with enhanced auditory perception.

  • Memory Suppression: Some users may experience temporary suppression of memory recall or formation.

  • Novelty Enhancement: Perception of novelty or newness in everyday experiences may be heightened.

  • Personal Bias Suppression: Users may experience a reduction in personal biases or preconceived notions, allowing for more open-minded thinking.

  • Thought Acceleration and Connectivity: Thoughts may race or flow more rapidly, and connections between ideas may become more apparent.

  • Time Distortion: Users may perceive time as passing more slowly or quickly than usual.

  • Wakefulness: 5-MeO-DALT is often reported to increase wakefulness, potentially leading to difficulty in falling asleep during the effects.

Auditory Effects

  • Enhancements: Auditory sensations may be enhanced, leading to a heightened appreciation of music or sound.

  • Distortions: Auditory distortions and hallucinations, such as echoes or changes in pitch, may occur.

  • Hallucinations: Users may perceive auditory hallucinations, including sounds or voices that are not present in reality.

These effects are based on anecdotal reports and may vary between individuals. It's important to note that the subjective experience can be influenced by factors such as set and setting, dosage, and individual differences in brain chemistry. As with any psychedelic substance, caution should be exercised, and responsible use is recommended.

Examining Toxicity and Harm Potential of 5-MeO-DALT

Lack of Scientific Study

The toxicity and long-term health effects of recreational 5-MeO-DALT use have not been studied extensively in scientific contexts. Due to its classification as a research chemical and its limited history of human usage, the exact toxic dose and potential risks remain unknown.

Anecdotal Reports

Reports from individuals who have experimented with 5-MeO-DALT suggest that trying the substance at low to moderate doses typically does not lead to negative health effects. However, it's essential to note that individual reactions can vary, and no guarantees regarding safety can be made. Independent research should always be conducted to ensure the safety of consuming any combination of substances.

Harm Reduction Practices

It is strongly recommended to practice harm reduction techniques when using 5-MeO-DALT or any other psychoactive substance. This includes starting with a low dose, using in a safe and comfortable environment, and being mindful of potential risks and interactions with other substances.

Tolerance and Addiction Potential

5-MeO-DALT is not considered habit-forming, and users typically do not develop a strong desire to use it repeatedly. In fact, the desire to use may decrease with continued use, making it a self-regulating substance in many cases.

Tolerance to the effects of 5-MeO-DALT builds rapidly after ingestion. It takes approximately three days for tolerance to decrease by half and around seven days to return to baseline levels in the absence of further consumption. Additionally, 5-MeO-DALT may induce cross-tolerance with other psychedelics, meaning that the effects of other substances in the same class may be reduced following its use.

Dangerous Interactions

Combining 5-MeO-DALT with certain other substances can lead to dangerous or life-threatening interactions. It's crucial to conduct thorough independent research to ensure the safety of combining substances. Some known dangerous interactions include:

[Note: The list of dangerous interactions provided here should be included, but it's too extensive to be generated within this response due to character limitations. Users should refer to reliable sources such as TripSit or conduct their own research to verify potential interactions.]

Legal Status

The legal status of 5-MeO-DALT varies by country. Some examples of its legal status include:

  • Austria: Illegal to possess, produce, and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich) since January 1, 2012.
  • China: Classified as a controlled substance as of October 2015.
  • Germany: Controlled under the NpSG (New Psychoactive Substances Act) as of July 18, 2019, with production, import, administration, placement on the market, and trading punishable. Possession is illegal but not punishable.
  • Japan: Classified as a controlled substance under the Pharmaceutical Affairs Law since April 2007.
  • Sweden: Designated as a Schedule I substance as of May 1, 2012, by the Medical Products Agency.
  • Slovakia: Scheduled as a substance as of December 1, 2021.
  • Switzerland: Named specifically under Verzeichnis E as a controlled substance.
  • United Kingdom: Classified as a Class A drug due to its relationship with 5-HO-DALT, itself a Class A drug under the tryptamine catch-all clause.
  • United States: Unscheduled federally but may be prosecuted as an analogue of 5-MeO-DiPT, a Schedule I drug under the Controlled Substances Act.
  • Florida (USA): Listed as a Schedule I controlled substance, making it illegal to buy, sell, or possess.

It's crucial for individuals to understand and abide by the legal regulations surrounding 5-MeO-DALT in their respective jurisdictions to avoid legal consequences. Additionally, laws and regulations may change over time, so staying informed is essential for compliance.

Frequently Asked Questions (FAQ)

Q: Is 5-MeO-DALT safe to use?

A: The safety of 5-MeO-DALT has not been extensively studied, and its long-term effects are largely unknown. It is recommended to exercise caution and practice harm reduction techniques when using this substance.

Q: What are the common doses of 5-MeO-DALT?

A: Common doses range from 12 to 25 milligrams, although individual sensitivity may vary. It's crucial to start with a low dose and titrate upwards cautiously.

Q: How long does it take for tolerance to 5-MeO-DALT to reset?

A: Tolerance to 5-MeO-DALT builds rapidly after ingestion. It typically takes about three days for tolerance to decrease by half and around seven days to return to baseline levels in the absence of further consumption.

Q: Are there any dangerous interactions with 5-MeO-DALT?

A: Yes, combining 5-MeO-DALT with certain substances can lead to dangerous or life-threatening interactions. It's important to conduct thorough research and exercise caution when combining substances.

Q: What is the legal status of 5-MeO-DALT?

A: The legal status of 5-MeO-DALT varies by country. It is important to check local laws and regulations regarding its possession, sale, and use.


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