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Introduction to 2C-B-FLY

2C-B-FLY, a lesser-known novel psychedelic compound belonging to the phenethylamine and benzodihydrodifuran classes, is recognized for its diverse range of psychedelic and entactogenic effects when administered. This article offers an in-depth exploration of 2C-B-FLY, shedding light on its properties, origins, and potential implications.

Uncovering its Unique Effects

Reports have characterized 2C-B-FLY's effects profile as a fusion of traits from 2C-B, mescaline, and MDA, delivering experiences that can last for a duration of 6 to 8 hours, with the possibility of extending up to 12 hours when consumed in larger doses.

A Derivative with Distinctions

2C-B-FLY is a derivative of the 2C-x family of psychedelic phenethylamines, notably differing from its counterpart, 2C-B, in terms of potency, metabolism, and potential toxicity. This intriguing compound had its origins in a synthesis by Aaron P. Monte in 1996.

A Journey Through Time

Around 2005, 2C-B-FLY surfaced and garnered some popularity within the online research chemicals market. However, it later fell into obscurity in October 2009 due to a tragic incident. A batch of Bromo-DragonFLY was mistakenly mislabeled as 2C-B-FLY. The critical distinction here is the dosing: Bromo-DragonFLY is measured in micrograms, whereas 2C-B-FLY is dosed in milligrams. This mix-up resulted in two fatalities due to overdoses of Bromo-DragonFLY, which were intended as effective doses of 2C-B-FLY. As a result, 2C-B-FLY was swiftly withdrawn from the market until it resurfaced around 2016.

The Enigma of 2C-B-FLY

Despite its availability, there is a scarcity of data regarding the pharmacological properties, metabolism, and toxicity of 2C-B-FLY. Additionally, it lacks an extensive history of human usage and has no documented presence in street markets. It is exclusively distributed through online research chemical vendors.

The Need for Precaution

The high potency and sensitive dose-response of 2C-B-FLY underscore the importance of handling this substance with caution. Many reports emphasize that its effects should not be viewed as a straightforward substitute for 2C-B. Therefore, if individuals choose to explore this potent, long-lasting, and unpredictable hallucinogenic substance, it is strongly recommended to approach it with a significant degree of precaution and embrace harm reduction practices.

Unraveling the Chemistry of 2C-B-FLY

2C-B-FLY, a member of the phenethylamine and dihydrobenzofuran chemical classes, features a phenyl ring linked to an amino (NH2) group via an ethyl chain. It also incorporates a bromine atom attached to carbon R4 of the phenyl ring.

This compound stands as an atypical psychedelic phenethylamine, sharing close resemblance to 2C-B. It acts as the dihydrofuran analog of 2C-B, with the methoxy groups from R2 and R5 of 2C-B integrated into five-member dihydrofuran rings fused to the central benzene ring. 2C-B-FLY is part of the FLY compounds, aptly named due to the insect-like appearance of two "wing-like" tetrahydrofuran rings fused on opposite sides of the central benzene ring. The positioning of the two methoxy groups within these five-member rings optimally facilitates their binding to the associated receptors, resulting in increased potency compared to the compound's non-rigid counterpart, 2C-B.

Peering into the Pharmacological Realm

2C-B-FLY falls within the category of psychedelic phenethylamines, serving as the dihydrodifuran analog of 2C-B. While much is yet to be understood about how it produces its effects, it is widely believed that 2C-B-FLY's psychedelic impact emanates from its activity at the 5-HT2A receptor as a partial agonist. Nonetheless, the precise mechanisms underlying these interactions and their role in engendering the psychedelic experience remain the subject of ongoing scientific investigation.

Subjective Effects: A Complex Tapestry

When compared to 2C-B, 2C-B-FLY distinguishes itself with a notably more pronounced body high/load, intensified visual effects, intricate geometric patterns, and in-depth internal hallucinations that bear semblance to experiences induced by mescaline, 2C-E, or MDA, especially at higher doses. Lower doses, conversely, are associated with entactogenic effects rather than classic psychedelic experiences.

Disclaimer: The effects described below are sourced from the Subjective Effect Index (SEI), a collection of anecdotal user reports and the personal analyses of contributors on PsychonautWiki. It is essential to approach these effects with a degree of skepticism, recognizing that they may not manifest predictably or reliably. Moreover, higher doses are more likely to encompass the full spectrum of effects, but they also elevate the risk of adverse effects, including addiction, severe injury, or even fatality.

Physical Effects

• Stimulation and Sedation: At light doses, 2C-B-FLY exhibits gentle, non-forceful stimulation, akin to the effects of 2C-B or mescaline. At higher doses, this stimulation may intensify to an uncomfortable level, often accompanied by sedation or lethargy, reminiscent of the experiences of 2C-C or 2C-T-7.
• Spontaneous Physical Sensations: The "body high" is characterized by a warm, all-encompassing tingling sensation, steadily intensifying from the onset until the peak is reached. It bears resemblance to the milder experiences of mescaline, 2C-B, or 2C-E.
  • Physical Euphoria
  • Tactile Enhancement
• Temperature Regulation Suppression: In comparison to 2C-B, 2C-B-FLY's influence on temperature regulation is notably more pronounced and unpredictable, with minor dose adjustments leading to significant changes in this effect.
  • Increased Bodily Temperature
• Bodily Control Enhancement
• Bodily Pressures
• Increased Blood Pressure
• Increased Libido
• Headaches: More frequently reported in comparison to 2C-B and other traditional phenethylamines.
• Muscle Cramps
• Stomach Bloating
• Stomach Cramps
• Nausea
• Diarrhea
• Dehydration
• Difficulty Urinating
• Excessive Yawning
• Watery Eyes
• Pupil Dilation
• Teeth Grinding

Visual Effects

• Enhancements
  • Colour Enhancement
  • Pattern Recognition Enhancement
  • Visual Acuity Enhancement
• Distortions
  • Drifting: Characterized by slow, smooth, intricate, and unrealistic/cartoon-like motion, akin to 2C-B or mescaline.
  • Tracers
  • After Images
  • Colour Shifting
  • Depth Perception Distortions
  • Perspective Distortions
  • Symmetrical Texture Repetition
• Geometry: Visual geometry closely resembles that of mescaline, 2C-B, and 2C-D, presenting intricate complexity, abstract forms, synthetic styles, structured organization, bright multicolored schemes, glossy shading, flat edges, large size, rapid motion, angular corners, non-immersive depth, and consistent intensity. The visuals exhibit a paradoxical blend of "natural" and "neon digital" characteristics, with higher doses more likely to induce level 8B visual geometry over level 8A.
• Hallucinatory States: 2C-B-FLY induces a moderate range of hallucinatory states akin to mescaline or standard doses of 2C-E. These experiences are more consistent and reproducible than those induced by many other commonly used psychedelics such as 2C-B or LSD. These states, typically occurring at heavier doses, seamlessly intertwine with the accompanying geometric patterns, encompassing transformations and internal hallucinations involving autonomous entities, settings, sceneries, perspectives, scenarios, and plots.

Conclusion: Navigating the 2C-B-FLY Experience

In this journey through the realm of 2C-B-FLY, we've explored its unique effects, distinctive chemistry, and the nuances of its subjective experiences. As an enigmatic substance with limited research and a checkered history, users are encouraged to approach 2C-B-FLY with care and embrace harm reduction practices. This comprehensive examination serves as a guide for those curious about this captivating but potentially potent hallucinogen.