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Product Name: 1P-LSD
IUPAC Name: (6aR,9R)-N,N-diethyl-7-methyl-4-propanoyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
Other Names: 1-propionyl-lysergic acid diethylamide
Cas Number: none
Molecular Formula: C23H29N3O2
Molar Mass: 379.501 g•mol-1
Effect: psychedelic, hallucinogen
Purity of the substance: 99.9%
Physical properties: liquid, blotters
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Table of Contents


In the realm of psychedelic substances, 1P-LSD has emerged as a captivating and enigmatic compound, sparking interest among researchers, psychonauts, and individuals intrigued by altered states of consciousness. With its potential to induce profound psychological experiences, 1P-LSD has become a subject of scientific inquiry and a fascination within the world of psychedelics. This article delves into the depths of 1P-LSD, shedding light on its nature, History, effects, dosages, legal Status, pharmacology, and chemistry.

How to get 1P-LSD

1P-LSD is not typically available through conventional outlets such as pharmacies or regulated retailers. It is primarily distributed through online research chemical vendors and the underground market. However, prospective users should exercise caution when considering purchasing any substance from unofficial sources, as the product's quality, purity, and legality can vary. Prioritizing thorough research and safety measures is crucial when seeking to acquire 1P-LSD. 


1P-LSD, formally known as 1-propionyl-lysergic acid diethylamide, is a synthetic compound that shares structural similarities with lysergic acid diethylamide (LSD), a classic and potent psychedelic substance. Chemically, 1P-LSD is an analog of LSD, with an additional propionyl group attached to its nitrogen atom. This subtle alteration has significant implications for its effects on the human mind.

The History of 1P-LSD

The History of 1P-LSD is intertwined with its parent compound, LSD. Developed in the 1930s, LSD gained prominence for its potent psychoactive effects and association with the counterculture movement of the 1960s. 1P-LSD, however, appeared much later, initially synthesized in 2006 by researchers at the University of Innsbruck, Austria. It was introduced as part of an investigation into the structure-activity relationships of LSD analogs.

Effects of 1P-LSD

The effects of 1P-LSD are akin to those of LSD, characterized by alterations in perception, mood, and cognition. Users commonly report vivid visual distortions, heightened sensory experiences, and a sense of interconnectedness with their surroundings. Additionally, 1P-LSD induces profound introspective states and enhanced emotional awareness. These effects are often accompanied by awe and wonder, making it a sought-after compound for those seeking profound psychedelic experiences.

Dosage of 1P-LSD

Determining an appropriate dosage of 1P-LSD is crucial to ensure a safe and meaningful experience. Dosages can vary widely and are typically measured in micrograms (μg). A threshold dose may start around 20-30 μg, while a moderate experience could range from 50-150 μg. Higher doses, exceeding 200 μg, are associated with more intense and immersive psychedelic states. As with any potent substance, users are advised to start with lower doses and gradually increase as needed while always prioritizing harm reduction practices.

Legal Status of 1P-LSD

The legal Status of 1P-LSD is complex and varies across different jurisdictions. In some regions, it exists within a legal grey area; in others, it is explicitly prohibited as a controlled substance. Before considering its use, individuals need to research and understand the legal Status of 1P-LSD in their country or region.

Pharmacology of 1P-LSD

1P-LSD's pharmacology is closely linked to its structural similarity to LSD. Upon ingestion, it undergoes metabolic processes that convert it into a compound that interacts with serotonin receptors in the brain, particularly the 5-HT2A receptor. This interaction alters perception, mood, and cognition, giving rise to the compound's psychedelic effects. The propionyl group present in 1P-LSD is thought to play a role in its metabolism and overall pharmacological profile.

Chemistry of 1P-LSD

From a chemical standpoint, 1P-LSD is a derivative of lysergic acid, a naturally occurring compound in the ergot fungus. Its full chemical name, 1-propionyl-lysergic acid diethylamide, reflects its structural composition. Adding the propionyl group to the nitrogen atom of LSD is a key modification that distinguishes 1P-LSD from its parent compound. This alteration is thought to affect its pharmaceutics and potency.

Final Thoughts

In the landscape of psychedelic exploration, 1P-LSD stands as a captivating compound with the potential to offer profound insights into the human mind and consciousness. Its structural resemblance to LSD, combined with its reported effects, has piqued the curiosity of researchers and enthusiasts alike. As the world of psychedelics continues to evolve, 1P-LSD remains an intriguing subject of investigation, offering a window into the intricate interplay between chemistry, perception, and the mysteries of the human psyche. Responsible exploration, comprehensive understanding, and adherence to safety guidelines are essential for those embarking on a journey with 1P-LSD. This compound continues to beckon seekers of altered states and expanded consciousness.


What is 1P-LSD?

1P-LSD, or 1-propionyl-lysergic acid diethylamide, is a synthetic compound with effects similar to LSD.

How is 1P-LSD different from LSD?

1P-LSD is an analog of LSD with an additional propionyl group, but its effects are quite similar to those of LSD.

Is 1P-LSD legal?

1P-LSD's legal status varies by location. It's important to research and understand the laws in your area.

What are the effects of 1P-LSD?

1P-LSD induces altered perception, mood, and cognition, often leading to vivid sensory experiences and introspection.

How do I take 1P-LSD?

1P-LSD is typically taken orally, often in the form of blotter paper. Follow harm reduction guidelines and start with a low dose.

Where can I get 1P-LSD?

1P-LSD is usually obtained from online research chemical vendors like the or underground markets.

What's the recommended dosage of 1P-LSD?

Dosages can vary, but a typical range is 20-150 micrograms (μg). Start with a lower dose and increase carefully.

What's the pharmacology of 1P-LSD?

1P-LSD's effects are linked to its interaction with serotonin receptors in the brain, especially the 5-HT2A receptor.

What's the history of 1P-LSD?

1P-LSD was first synthesized in 2006 as part of LSD analog research, distinct from LSD's history dating back to the 1930s.

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