Buy 6-APB (Benzofury) for sale online - USA vendor

Table of Contents

1. Introduction
2. History and Cultural Significance
   • Initial Synthesis and Purpose
   • Emergence in the Research Chemical Market
   • Legal Classification in the UK
3. Chemical Structure and Properties
   • Chemical Composition of 6-APB
   • Comparison with Related Compounds
   • Different Forms of 6-APB
4. Pharmacology and Effects
   • Subjective Effects
   • Pharmacological Properties
5. Safety, Toxicity, and Harm Reduction
6. Conclusion

Introduction

6-(2-Aminopropyl)benzofuran, commonly known as 6-APB or "Benzofury," is a novel synthetic substance belonging to the benzofuran class. It is closely related to well-known entactogens such as MDA (3,4-Methylenedioxyamphetamine) and MDMA (3,4-Methylenedioxymethamphetamine). 6-APB gained attention in recreational use due to its ability to induce euphoria, empathy, and a range of psychoactive effects.

Originally synthesized in 1993 by the chemist David E. Nichols, 6-APB was designed as a potential alternative to MDMA, with the hope of reducing neurotoxic side effects. However, it was not until much later that it entered the recreational drug scene, briefly becoming a popular choice among users before being banned in many regions.

History and Cultural Significance

Initial Synthesis and Purpose

6-APB was first synthesized in 1993 by a team led by David E. Nichols at Purdue University. Nichols and his team were investigating the role of MDA's dioxole ring structure in serotonin interaction within the brain. This research was partly motivated by the rising concerns over the neurotoxic effects of MDMA, which was gaining popularity for both recreational use and potential therapeutic benefits.

Nichols aimed to create a safer, non-neurotoxic alternative to MDMA that could provide similar therapeutic and entactogenic effects without the associated risk of long-term harm to the brain. Despite this, human usage of 6-APB did not surface until many years later.

Emergence in the Research Chemical Market

6-APB emerged on the research chemical market around 2010. It gained significant popularity in the United Kingdom, where it was sold as a "legal high" under the name "Benzofury." Its similarity to MDMA and MDA made it a sought-after substance for those seeking the effects of these illegal drugs but wanting to avoid legal consequences.

At the time, 6-APB and other novel benzofuran derivatives like 5-APB and 5-MAPB were marketed as legal alternatives to MDMA. These substances were sold by online research chemical vendors and were particularly attractive in the underground rave scene.

Legal Classification in the UK

The legality of 6-APB was short-lived in many countries, particularly the UK. On June 10, 2013, 6-APB and several related compounds were classified as Temporary Class Drugs following recommendations by the Advisory Council on the Misuse of Drugs (ACMD). This temporary ban was later solidified when, in November 2013, the ACMD recommended making 6-APB and other benzofuran compounds Class B, Schedule 1 substances. This recommendation was enacted on June 10, 2014, when 6-APB was officially classified as a Class B drug, along with other structurally related compounds.

Chemical Structure and Properties

Chemical Composition of 6-APB

6-APB is a synthetic molecule that belongs to the benzofuran class of chemicals. Substances in this class are related to both the amphetamine and phenylethylamine families. Structurally, 6-APB consists of a phenethylamine core, which is bound to an amino (NH2) group via an ethyl chain. The compound also features a benzofuran ring fused to the phenyl ring at positions R3 and R4.

Unlike some related substances, 6-APB lacks a methyl substitution on its nitrogen atom (RN), which sets it apart from other amphetamines and phenethylamines.

Comparison with Related Compounds

6-APB shares structural similarities with other benzofuran compounds such as 5-APB, 5-MAPB, and 6-MAPB. The benzofuran ring present in 6-APB is the defining feature of these compounds, distinguishing them from more traditional amphetamines. This shared structure also contributes to their comparable effects, which include mood enhancement, empathy, and euphoria, all hallmarks of the entactogenic class.

Different Forms of 6-APB

Since its introduction to the research chemical market, 6-APB has been available in three distinct forms. Initially, only the hydrochloride salt form of 6-APB was sold. This version shared many characteristics with MDA, particularly in terms of its dose-response profile. Later, succinate and fumarate forms of 6-APB were introduced to the market. These variations differ significantly in terms of potency by weight and bulk density, with each form producing slightly different effects.

Pharmacology and Effects

Subjective Effects

The effects of 6-APB are often compared to those of other entactogens like MDA and MDMA. Users report experiencing a range of effects, including:

• Euphoria: Intense feelings of happiness and well-being.
• Empathy: Heightened emotional sensitivity and connection with others.
• Disinhibition: Lowering of social inhibitions, often making users feel more open and talkative.
• Anxiety suppression: A noticeable reduction in anxiety levels during the experience.
• Muscle relaxation: Physical relaxation, which contrasts with the more stimulating effects of amphetamines.

However, 6-APB can also produce negative effects, particularly at higher doses or with repeated use. These may include nausea, restlessness, and mild hallucinations.

Pharmacological Properties

Very little research exists regarding the exact pharmacological profile of 6-APB. It is believed to act as a serotonin, norepinephrine, and dopamine reuptake inhibitor, similar to other entactogens. This action increases the levels of these neurotransmitters in the brain, leading to the mood-enhancing and empathogenic effects users experience.

Safety, Toxicity, and Harm Reduction

Due to the lack of extensive scientific studies on 6-APB, its toxicity profile remains largely unknown. There is very limited data regarding its long-term effects on human health. Users are advised to practice harm reduction techniques, such as using accurate dosing scales, avoiding combinations with other substances, and spacing out doses to avoid building tolerance or experiencing adverse side effects.

Because of its similarity to MDMA and MDA, which have been linked to neurotoxicity and other health risks when used excessively, it is possible that 6-APB carries similar risks. Users should exercise caution and be aware of the potential dangers associated with its use.

Conclusion

6-APB, or "Benzofury," is a synthetic entactogen with a brief but notable presence in the research chemical market. Originally synthesized as a potential alternative to MDMA, it became popular for its ability to induce feelings of euphoria, empathy, and relaxation. However, its lack of extensive safety data, combined with its legal status as a controlled substance in many countries, makes it a high-risk option for recreational use. As with many novel psychoactive substances, caution and harm reduction practices are highly recommended for those considering its use.

6-APB and "Benzofury" – Frequently Asked Questions (FAQ)

1. What is 6-APB?

6-APB, or 6-(2-Aminopropyl)benzofuran, is a synthetic compound belonging to the benzofuran class of chemicals. It is structurally related to MDMA and MDA and is known for its mood-enhancing, euphoric, and empathogenic effects.

2. What is "Benzofury"?

"Benzofury" is the street name for 6-APB. It was marketed as a "legal high" in the early 2010s, especially in the UK, before it was banned.

3. How does 6-APB work?

6-APB likely works by inhibiting the reuptake of serotonin, norepinephrine, and dopamine, increasing their levels in the brain. This action enhances mood, creates euphoria, and induces feelings of empathy.

4. What are the effects of 6-APB?

The effects of 6-APB include euphoria, enhanced empathy, reduced anxiety, muscle relaxation, and disinhibition. It is often compared to MDMA, though some users describe it as slightly more relaxing.

5. How long do the effects of 6-APB last?

The effects of 6-APB typically last 6-10 hours, with the peak of the experience occurring around 2-4 hours after ingestion.

6. Is 6-APB legal?

6-APB is illegal in many countries. In the UK, it was classified as a Class B drug in 2014. Its legal status varies by country, so it’s important to check local regulations.

7. What are the risks or side effects of using 6-APB?

Common side effects of 6-APB include nausea, headaches, restlessness, difficulty sleeping, and mild hallucinations. Long-term risks are not well understood due to limited research, but its similarity to MDMA suggests potential neurotoxicity with chronic use.

8. Is 6-APB safe to use?

There is limited data on the safety of 6-APB. Like other research chemicals, it carries unknown risks, and users are advised to follow harm reduction practices. These include using accurate dosing, avoiding combining with other substances, and taking breaks between uses.

9. How does 6-APB compare to MDMA?

6-APB and MDMA have similar effects, including euphoria, enhanced empathy, and disinhibition. However, some users find 6-APB to be more sedating and longer-lasting than MDMA.

10. Can 6-APB cause addiction?

There is limited information on the addiction potential of 6-APB. However, like MDMA, it may lead to psychological dependence if used frequently due to its mood-enhancing properties.

11. How is 6-APB typically taken?

6-APB is usually consumed orally in the form of powder, capsules, or tablets. Less commonly, some people snort the substance, though this is often associated with stronger side effects.

12. What is the recommended dosage for 6-APB?

The typical dosage range for 6-APB is 80-130 mg when taken orally. However, dosage may vary depending on the form (succinate, fumarate, or hydrochloride), and individual tolerance.

13. What are the different forms of 6-APB?

6-APB has been sold in three main forms: hydrochloride, succinate, and fumarate. These forms differ in terms of potency by weight and loose bulk density.

14. Is 6-APB detectable in drug tests?

6-APB is not commonly tested for in standard drug screenings. However, specialized tests may detect its metabolites, particularly in extended drug panels.

15. How does 6-APB affect serotonin levels?

Like MDMA, 6-APB increases serotonin levels in the brain by inhibiting its reuptake. This boost in serotonin is responsible for many of the substance's mood-enhancing and empathogenic effects.

16. Can 6-APB cause serotonin syndrome?

Yes, 6-APB can potentially cause serotonin syndrome, especially when combined with other serotonergic drugs like SSRIs or other entactogens. Serotonin syndrome is a serious condition and can be life-threatening, so combining substances should be avoided.

17. Is there a comedown from 6-APB?

Many users report a comedown after using 6-APB, similar to MDMA. Symptoms may include fatigue, low mood, and irritability in the days following use, commonly referred to as "the crash."

18. Can 6-APB be mixed with other substances?

It is not advisable to mix 6-APB with other substances, especially other stimulants, entactogens, or serotonin-affecting drugs. Mixing can increase the risk of serotonin syndrome and other dangerous side effects.

19. What harm reduction practices should be followed when using 6-APB?

Harm reduction practices include accurate dosing with a milligram scale, using the substance in a safe environment, staying hydrated, avoiding other drugs, and allowing time for recovery between uses.

20. How long does 6-APB stay in your system?

The exact duration that 6-APB stays in the body is not well known, but its effects last 6-10 hours. It could take a couple of days for the substance to fully clear from the system, depending on metabolism and frequency of use.