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Product Name: 4-Aco-DMT
IUPAC Name: 4-Acetoxy-N,N-dimethyltryptamine, 3-(2'-dimethylaminoethyl)-4-acetoxy-indole
Other Names: psilacetin, 4-acetoxy-DMT, 4-AcO-DMT
Cas Number: 92292-84-7
Molecular Formula: C14H18N2O2
Molar Mass: 246.3049 g/mol
Effect: Psychedelics
Purity of the substance: 99.9%
Physical properties: Crystalline powder
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In the realm of psychedelic substances, 4-AcO-DMT has emerged as a captivating and enigmatic compound. With its potential to induce profoundly altered states of consciousness and unique psychological experiences, 4-AcO-DMT has garnered attention from researchers, psychonauts, and those curious about the human mind. This article delves into the depths of 4-AcO-DMT, shedding light on its nature, History, effects, dosages, legal Status, pharmacology, and chemistry.


Table of Contents

How to get 4-AcO-DMT

4-AcO-DMT is not readily available through conventional channels, such as pharmacies or licensed retailers. It is primarily distributed through online research chemical vendors and the underground market. However, caution is advised when considering purchasing any substance from unofficial sources, as the product's quality, purity, and legality may be questionable. Conducting thorough research and prioritizing safety is paramount when acquiring 4-AcO-DMT. 

The History of 4-AcO-DMT

The origins of 4-AcO-DMT trace back to the mid-20th century when its chemical structure was first synthesized by Dr. Albert Hofmann, the same chemist who discovered LSD. However, its psychoactive properties remained largely unexplored until more recent times. In the early 21st century, 4-AcO-DMT gained prominence within the psychedelic research and enthusiast communities, sparking interest due to its reported effects similar to psilocybin mushrooms.

Effects of 4-AcO-DMT

The effects of 4-AcO-DMT are often described as a blend of classic psychedelic experiences and introspective journeys. Users commonly report altered sensory perceptions, enhanced emotional states, and profound insights into their thoughts and feelings. Visual distortions, such as drifting patterns and color changes, are also frequent, reminiscent of those induced by psilocybin-containing mushrooms. The compound's effects can vary based on dosage, set and setting, and individual differences, making each experience unique.

Dosage of 4-AcO-DMT

Determining a dosage of 4-AcO-DMT is crucial to ensure a safe and enjoyable experience. Dosages can vary widely and are often measured in milligrams (mg). Threshold doses may start around 5-10 mg, while moderate experiences typically range from 10-20 mg. Higher doses, ranging from 20-40 mg or more, are associated with more intense and immersive psychedelic states. Due to its potency, users should start with lower doses and gradually increase as needed while adhering to harm reduction principles.

Legal Status of 4-AcO-DMT

The legal Status of 4-AcO-DMT varies from country to country. In some regions, it is classified as a controlled substance, making its possession, distribution, and use illegal. In other areas, its legal Status needs to be clarified or unregulated. Individuals must research and understand the legal Status of 4-AcO-DMT in their jurisdiction before considering its use.

Pharmacology of 4-AcO-DMT

The pharmacology of 4-AcO-DMT is intricately linked to its molecular structure. After ingestion, the compound is rapidly metabolized into its active form, psilocin. Psilocin interacts with serotonin receptors in the brain, particularly the 5-HT2A receptor, leading to alterations in perception, mood, and cognition. This mechanism of action is shared with other classic psychedelics and is believed to underlie the compound's psychedelic effects.

Chemistry of 4-AcO-DMT

From a chemical standpoint, 4-AcO-DMT belongs to the tryptamine class of compounds characterized by a core indole structure. Its full chemical name is 4-Acetoxy-N, N-dimethyltryptamine. The acetoxy group attached to the indole ring plays a significant role in the compound's pharmacological and psychoactive properties. This subtle modification allows 4-AcO-DMT to be metabolized into psilocin more efficiently than other synthetic tryptamines, contributing to its potency and psychedelic effects.

Final point

In the realm of psychedelic exploration, 4-AcO-DMT stands as a compelling compound with the potential to offer profound insights into the human mind. Its structural similarity to psilocybin and its reported effects have ignited interest among researchers, enthusiasts, and those seeking to delve into altered states of consciousness. As with any psychoactive substance, responsible use, thorough research, and adherence to safety guidelines are paramount.

While the History, effects, dosages, legal Status, pharmacology, and chemistry of 4-AcO-DMT provide a comprehensive understanding of the compound, it is essential to approach its exploration with caution and respect. As the landscape of psychedelic research continues to evolve, 4-AcO-DMT remains a captivating subject of investigation, offering a window into the intricate workings of the human psyche and its connection to the mysteries of the mind.


1. What is 4-AcO-DMT?

4-AcO-DMT, or 4-Acetoxy-N,N-dimethyltryptamine, is a synthetic compound with psychedelic properties similar to psilocybin mushrooms.

2. How Can I Obtain 4-AcO-DMT?

4-AcO-DMT is primarily obtained through online research chemical vendors and the underground market. Exercise caution when purchasing from unofficial sources.

3. What Are the Effects of 4-AcO-DMT?

Users report altered sensory perceptions, enhanced emotional states, visual distortions, and profound insights into thoughts and feelings.

4. What Is the Typical Dosage of 4-AcO-DMT?

Dosages can vary, but threshold doses start around 5-10 mg, while moderate experiences range from 10-20 mg. Higher doses (20-40 mg or more) are associated with more intense effects.

5. What Is the Legal Status of 4-AcO-DMT?

Legal status varies by country. In some regions, it's a controlled substance, while in others, its status is unclear or unregulated. Research the legal status in your jurisdiction.

6. How Does 4-AcO-DMT Work (Pharmacology)?

4-AcO-DMT is rapidly metabolized into psilocin, which interacts with serotonin receptors in the brain, leading to altered perception, mood, and cognition.

7. What Is the Chemistry of 4-AcO-DMT?

4-AcO-DMT belongs to the tryptamine class of compounds. Its chemical name is 4-Acetoxy-N,N-dimethyltryptamine. The acetoxy group enhances its psychoactive properties.

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