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The novel psychoactive substance 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)butan-1-one (5-PPDI) was first identified in 2015 as a new psychoactive substance. 5-PPDI is an indanyl analog of α-PBP, a typical synthetic cathinone, and the aliphatic ring analog of MDPBP, a synthetic cathinone with a heterocyclic ring. In this study, 5-PPDI and its three regioisomers were synthesized from commercially available precursor compounds and analyzed by gas chromatography/electron ionization–quadrupole mass spectrometry (GC/EI–Q-MS) and by liquid chromatography/electrospray ionization–linear ion trap mass spectrometry (LC/ESI–LIT–MS).
1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)butan-1-one (5‑PPDI), a new psychoactive substance, was first identified in 2015. 5‑PPDI is an indanyl analog of α‑PBP, a typical synthetic cathinone, and the aliphatic ring analog of MDPBP, a synthetic cathinone with a heterocyclic ring. In this study, 5‑PPDI and its three regioisomers were synthesized from commercially available precursor compounds and analyzed by gas chromatography/electron ionization–quadrupole mass spectrometry (GC/EI–QMS) and by liquid chromatography/electrospray ionization–linear ion trap mass spectrometry (LC/ESI–LIT–MS).
As synthetic cathinones, such as α-PBP and MDPBP, continue to rise, it is necessary to develop methods for identifying new substances. 5-PPDI with its three regioisomers was synthesized from commercially available precursor compounds and analyzed by GC/EI–Q-MS and LC/ESI–LIT–MS.
5-PPDI is a synthetic cathinone created chemically in different forms.
A novel psychoactive substance, 5-PPDI (1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)butan-1-one), was first identified in 2015. 5-PPDI can have three regioisomers, and here we synthesized them from commercially available precursor compounds and analyzed their chemical structures by LC/ESI–LIT–MS and GC/EI–QMS.
Looking for online research chemicals 5-PPDI vendor USA
This study deals with the synthesis and analysis of the new psychoactive substances 5-PPDI (1-(2,3-dihydro-1H-in-5-yl)-2-(pyrrolidine-1-yl)butane-1-one), 1-(2,3-dihydro-1H-in-1-yl)-2-(pyrrolidine-1-yl)butanone, 1-(2,3-dihydro-1H indium 2 -yl)-2-(pyrrolidine -1 -yl)butanone and 1 –(2,3 indium 4 –y l )–2 –( pyrrolidine - yl)butanone by gas chromatography/electron ionization–quadrupole mass spectrometry (GC/EI–QMS), liquid chromatography/electrospray ionization–linear ion trap mass spectrometry.
This article presents the results of research work on the preparation and characterization of new psychoactive substances: 5-(1-indan)-2-((pyrrolidin-1-yl)butanone (1), 1-(2,3 indanyl)-2–(pyrrolidin-1-yl)butanone (2), 5-(1-inden)- 2-(pyrrolidin-1-yl)butanone (3) and 1-(2,3 inden)-4–(pyrrolidine-1yl)butanone (4).
A substrate-controlled, four-component reaction of o-phenylenediamine, HCl salt of 1-(2-aminobutyl)-2-pyrrolidine carboxylic acid, 1,2-dihydro-1H-indene and acetic acid was carried out in n-pentane at 180°C for 30 min to provide the aminoalkyl (dialkyl) indene carboxamides. This is a novel synthetic route for the preparation of alkyl indenes.
This paper presents the synthesis and characterization of five new synthetic cannabinoids identified from counterfeit tablets sold as designer drugs.
We attempt to synthesize and characterize the regioisomers of 5-PPDI, including 1-PPDI, 2-PPDI, and 4-PPDI. GC/EI analyzed the prepared compounds–Q-MS and LC/ESI–LIT–MS methods.
This study identified 5-PPDI and its possible regioisomers. Detecting this novel synthetic cathinone is important because it can be used as a potential alternative to scheduling I-controlled drugs such as MDPBP and α-PBP.
The present study aimed to prepare and analyze 5-PPDI and its three regioisomers by synthetic means and to identify their regioisomers.
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