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The best way to buy Phenethylamine (PEA) for sale
Phenethylamine (PEA) is an organic compound, a natural monoamine alkaloid, and a trace amine. Its effects as a stimulant within the central nervous system of humans are well-documented. Within the brain, phenethylamine takes on the role of regulating monoamine neurotransmission. This is achieved by binding to the trace amine-associated receptor 1 (TAAR1) while inhibiting the vesicular monoamine transporter 2 (VMAT2) found in monoamine neurons. It also assumes a lesser role as a neurotransmitter within the human central nervous system.
In mammals, the enzyme aromatic L-amino acid decarboxylase facilitates the transformation of phenethylamine from the amino acid L-phenylalanine through enzymatic decarboxylation. Beyond mammals, phenethylamine is present in various other organisms and foods, notably chocolate, especially after microbial fermentation.
Phenethylamine is marketed and sold as a dietary supplement with suggested therapeutic benefits for mood enhancement and weight loss. However, when orally consumed, a significant portion of ingested phenethylamine is metabolized in the small intestine by monoamine oxidase B (MAO-B) and subsequently by aldehyde dehydrogenase (ALDH). This metabolic process converts phenethylamine into phenylacetic acid. Consequently, higher dosages are required to achieve substantial concentrations of phenethylamine in the brain compared to alternative administration methods. Some authors have speculated about its potential role in the experience of falling in love, although these claims lack direct supporting evidence.
Substituted phenethylamines, or phenethylamine derivatives, comprise a class known for containing the phenethylamine "backbone." Essentially, this chemical category encompasses derivative compounds created by covering one or more hydrogen atoms in the phenethylamine core structure with substituents. Within the realm of substituted phenethylamines, one finds various substituted amphetamines and substituted methylenedioxyphenethylamines (MDxx). This class also features numerous drugs with functions spanning empathogens, stimulants, psychedelics, anorectics, bronchodilators, decongestants, antidepressants, and more.
